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A mass brawl on a popular Auckland nightlife strip has ended with multiple arrests and a person in hospital with critical injuries.

Police were called to Auckland’s Karangahape Rd just after 3.30am following multiple reports of a mass disorder and large fight on the street.

Officers attended to disperse the crowd of around 50 people.

Hato Hone St John sent an ambulance to the scene, where one person had been critically injured and was taken to hospital for treatment.

Police said four people were arrested in connection to the fight.

The Karangahape Rd and Cobden St intersection, by the base of the Lighthouse Apartments, has been taped off as police investigate.

Police scene examination on K Road after a large fight took place in the early hours of this morning. Photo / Dean Purcell

A forensic examination is taking place. Photo / Dean Purcell

Residents reported hearing yelling and screaming on the street for approximately two hours following the incident, as armed police searched the area with dogs.

A worker at Sunshine Superette said he arrived to open the store and came across the heavy police presence nearby, but was soon able to open for trade.

Businesses along Karangahape Rd had been notified of the incident, he said.

A couple residing in the area said they heard dogs barking through the night, but weren’t aware of what had unfolded until this morning.

A large nitrous oxide canister box can be seen on the ground outside the Lighthouse Apartments.

Forensic officers and detectives are still visible in the area this morning.

The Karangahape Rd and Cobden St intersection, by the base of the Lighthouse Apartments, has been taped off. Photo / Dean Purcell